OECD 423 OECD Guidelines for the Testing of Chemicals, Acute Oral Toxicity, Acute Toxic Class Method

Chemical Tests

OECD 423 OECD Guidelines for the Testing of Chemicals, Acute Oral Toxicity, Acute Toxic Class Method

EUROLAB laboratory provides testing and compliance services within the scope of OECD 423 standard. The OECD chemicals testing guidelines are a collection of approximately 150 of the most relevant internationally recognized test methods used by government, industry and independent laboratories to identify and characterize the potential hazards of chemicals.

OECD 423 OECD Guidelines for the Testing of Chemicals, Acute Oral Toxicity, Acute Toxic Class Method

They are a set of tools for professionals used primarily in regulatory safety testing and then in chemical and chemical product declaration, chemical registration and chemical evaluation. They can also be used for selection and sequencing of candidate chemicals during the development of new chemicals and products and in toxicology research. This set of tests covers health effects.

A stepwise procedure using a minimum number of animals per step is used to obtain sufficient information on the acute toxicity of the chemical to enable classification.

The chemical is administered orally to a group of rodents at one of the defined doses. Each step of the step-by-step procedure consists of three rodents of a single sex (typically females). The absence or presence of compound-related mortality dosed in one step will determine the next step.

EUROLAB assists manufacturers with OECD 423 test compliance. Our test experts, with their professional working mission and principles, provide you, our manufacturers and suppliers, the best service and controlled testing process in our laboratories. Thanks to these services, businesses receive more effective, high-performance and quality testing services and provide safe, fast and uninterrupted service to their customers.

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