EUROLAB laboratory provides testing and compliance service within the scope of OECD 473 standard. The purpose of in vitro chromosome aberration testing is to identify agents that cause structural chromosome aberrations in cultured mammalian somatic cells.
In vitro chromosome aberration testing may use cultures of established cell lines, cell strains, or primary cell cultures. Cell cultures are exposed to the test substance (liquid or solid) both with and without metabolic activation for approximately 1.5 normal cell cycle lengths.
At least three analyzable concentrations of the test substance should be used. Duplicates should normally be used at each concentration.
At predetermined intervals after exposure of the cell cultures to the test substance, the cells are treated with a metaphase-retaining agent, harvested, stained. Metaphase cells are analyzed microscopically for the presence of chromosome aberrations.
EUROLAB assists manufacturers with OECD 473 test compliance. Our test experts, with their professional working mission and principles, provide you, our manufacturers and suppliers, the best service and controlled testing process in our laboratories. Thanks to these services, businesses receive more effective, high-performance and quality testing services and provide safe, fast and uninterrupted service to their customers.
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EUROLABreporting and certification activities, United Accreditation Foundation (UAF), Turkish Accreditation Agency (TÜRKAK) ve Enterprise Accreditation Foundation (EAF) based on the accreditation provided by the accreditation body. The Enterprise Accreditation Foundation (EAF) accreditation body is also a signatory of the United Nations (UN GLOBAL COMPACT) organization.
