OECD 203 OECD Guidelines for the Testing of Chemicals - Part 203: Fish - Acute Toxicity Testing

Chemical Tests

OECD 203 OECD Guidelines for the Testing of Chemicals - Part 203: Fish - Acute Toxicity Testing

EUROLAB, with its state-of-the-art accredited laboratories and expert team, provides precise and fast testing services within the scope of OECD 203 testing. The OECD chemicals testing guidelines are a collection of approximately 150 of the most relevant internationally recognized test methods used by government, industry and independent laboratories to identify and characterize the potential hazards of chemicals.

OECD 203 OECD Guidelines for the Testing of Chemicals - Part 203: Fish - Acute Toxicity Testing

They are a set of tools for professionals used primarily in regulatory safety testing and then in chemical and chemical product declaration, chemical registration and chemical evaluation. They can also be used to select and rank candidate chemicals during the development of new chemicals and products and in toxicology research. This group of tests covers effects on biotic systems.

The fish is preferably exposed to the test substance for a period of 96 hours. Deaths are recorded at 24, 48, 72, and 96 hours, and concentrations (LC50) that kill 50 percent of the fish, if possible, are determined. One or more species may be used, selection is at the discretion of the testing laboratory. At least seven fish should be used at each test concentration and controls.

This study includes observations of fish at least 24, 48, 72 and 96 hours later. The cumulative percent mortality for each exposure period is plotted against the concentration on the logarithmic probability sheet. The fish is preferably exposed to the test substance for a period of 96 hours. Deaths are recorded at 24, 48, 72, and 96 hours, and concentrations (LC50) that kill 50 percent of the fish, if possible, are determined.

EUROLAB assists manufacturers with OECD 203 test compliance. Our test experts, with their professional working mission and principles, provide you, our manufacturers and suppliers, the best service and controlled testing process in our laboratories. Thanks to these services, businesses receive more effective, high-performance and quality testing services and provide safe, fast and uninterrupted service to their customers.

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